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Ultra HNS
  Hair Nails Skin Formula
Remarkable Supplement by Douglas Laboratories
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Note: HMS Crown no longer stocks vitamin and health supplements with the exception of Ultra HNS for beautiful hair, skin, and nails. WHAT IS HNS?

Ultra HNS by Douglas Laboratories supplies high dose biotin, methylfolate, vitamin C, zinc, and Cynatine®
HNS, a patented, solubilized keratin for the health of hair, nails, and skin. Cynatine® HNS has demonstrated
that it can improve the strength, brightness and appearance of hair, nails and skin as well as reduce hair loss
associated with washing.

Keratin is a protein found throughout the body and has an important structural role in skin, hair, nails. This
intriguing protein also has one of the highest proportions of the amino acid cysteine, a natural reservoir of
sulphur and an antioxidant used in many biological reactions. Much of the structural strength of keratin comes
from cysteines, which bridge to form a cystine link. The ability to convert natural keratin into a functional form
that is bio-available to the body is a recent breakthrough. A patented process now enables the intact keratin
molecule to be solubilized, therefore making it both bioactive and bio-available to the body.

Cynatine® HNS is a natural bioactive keratin extracted from premium quality pure New Zealand wool using a
unique patented process. Cynatine® HNS has demonstrated that it can improve the strength and appearance
of hair as well as reduce hair loss associated with washing. It has also been shown to be capable of
supporting healthy skin aging as well as improving the strength and luster of nails. A major component of the
skin moisture barrier is cysteine-rich keratin. Damage to the keratin in this barrier can also result in increased
skin wrinkles. In vitro studies show Cynatine® HNS supports cell proliferation and protein synthesis of human
skin keratinocytes. Cell proliferation is used as a marker of cell growth and turnover. A clinical study was
performed on Cynatine® HNS which showed that after 90 days, hair loss from washing was reduced by 30%,
hair strength was improved by 12%. Additionally, participants reported improvements in both the shine and
brightness of their hair. The ability of Cynatine® HNS to protect the skin from oxidative stress has been
determined through a combination of in vitro and in vivo measurement. Experimental data reveals that
ingested Cynatine® HNS helps to build the cells' glutathione supply, resulting in an increase in serum levels of
glutathione-dependent peroxidase.

Vitamin C (ascorbic acid) has numerous biological functions. Foremost, it is essential for the synthesis of
collagen and glycosaminoglycans which are the building materials of all connective tissues, such as skin,
blood vessels, tendons, joint cartilage and bone. Vitamin C is the required coenzyme for two groups of
enzymes that catalyze the crosslinking of collagen fibers - lysyl hydroxylases and prolyl hydroxylases. As such,
vitamin C is essential for normal wound healing and capillary health.
Zinc is important for growth, immune system function, protein synthesis, antioxidant mechanisms, and wound
healing. Both zinc and copper, once bound to either a protein or peptide, have been shown to be very effective
in regenerating new tissue and increasing the synthesis of structural proteins like collagen.
Biotin is a B vitamin that is found in small amounts in numerous foods. Biotin deficiency is difficult to detect
because of the lack of assay techniques to determine biotin concentrations in the blood. Symptoms of
deficiency include thinning of the hair, frequently with loss of hair color, and red scaly rash around the eyes,
nose, and mouth. Biotin supplementation after 5 months has been clinically shown to support nail firmness
and thickness and to reduce splitting in several studies. Folate is another B vitamin that is essential for tissue
growth and cellular functions. Ultra HNS uses Metafolin® folate, a brand name L-methylfolate form that the
body readily utilizes without the conversion of folic acid to L-methylfolate. Clinical evidence indicates that the
bioavailability of Metafolin® is superior to folic acid. PABA supports the appearance of healthy hair, through its
effects on melanin metabolism. Melanin, or pigment, is a substance that gives hair and skin its color.

Serving size 3 vegetarian capsules
Vitamin C .....................................250 mg
(as Ascorbic Acid)
Folate .........................................200 mcg

(as L-Methylfolate, Metafolin®)
Biotin .......................................6,000 mcg
Zinc (Krebs*)...................................25 mg
Cynatine® HNS ............................500 mg

(soluble keratin)
PABA .............................................75 mg
(Para-Aminobenzoic Acid)
Lemon Bioflavonoid Complex.........75 mg

Other ingredients: Hydroxypropyl methylcellulose (capsule), dicalcium phosphate, cellulose, vegetable stearate
and silica

*Krebs = Citrate, Fumarate, Malate, Glutarate and Succinate Complex.


Adults take 3 capsules daily or as directed by your health care professional. This product is best taken with

No adverse effects have been reported.

Store in a cool, dry place, away from direct light. Keep out of reach of children.


Sano T, Kume T, Fujimura T, Kawada H, Moriwaki S, Takema Y. The formation of wrinkles caused by transition of keratin
intermediate filaments after repetitive UVB exposure. Arch Dermatol Res. 2005 Feb;296(8):359-65.

Matsuo M, Ikeda H, Sugihara T, Horiike S, Okano Y, Masaki H. Resistance of cultured human skin fibroblasts from old and
young donors to oxidative stress and their glutathione peroxidase activity. Gerontology. 2004 Jul-Aug;50(4):193-9.

Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6,
Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000

Floersheim GL. Treatment of brittle fingernails with biotin. Z Hautkr 1989;64:41–8 [in German].

Hochman LG, Scher RK, Meyerson MS. Brittle nails: response to daily biotin supplementation. Cutis 1993;51:303–5.

Antony AC. Megaloblastic Anemias. In: Hoffman R, Benz Jr EJ, Shattil SJ, et al. Hematology: Basic Principles and
Practice. 3rd ed. New York, NY: Churchill Livingstone 2000: 451-79.

Zarafonetis CJ. Darkening of gray hair during para-amino-benzoic acid therapy. J Invest Dermatol 1950;399-401.

These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Manufactured by
Douglas Laboratories

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